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pSoBid is a cross sectional population-based study which set out to investigate the psychological, behavioural and biological determinants of ill-health

pSoBid aims to explore the extent to which the syndrome of central obesity/chronic inflammation contributes to the social gradient in vascular disease and is associated with variation in mental outlook.

In a recruited cross-sectional group of participants from the least deprived and most deprived areas of Glasgow, the study aims to examine:

  • the relationship between markers of biological age and chronological age
  • the relationships between biological ageing (as measured by IMT and telomere length) and (i) early life and current socioeconomic status, (ii) biochemical markers of inflammation, (iii) health-related behaviours, (iv) psychological profile, (v) cognitive function and (vi) risk of vascular disease
  • the relationships between chronic inflammation and (i) early life and current socioeconomic status, (ii) cognitive function, (iii) psychological profile, (iv) neuro-images and (v) risk of vascular disease.

 

Journal Articles

 


openaccess new

Psychological, social and biological determinants of ill health (pSoBid): study protocol of a population-based study. 
Yoga N Velupillai, Chris J Packard CJ, G David Batty, Vladimir Bezylak, Harry Burns H, Jonathan Cavanagh, Kevin Deans, Ian Ford, Agnes McGinty, Keith Millar, Naveed Sattar, Paul Shiels, Carol Tannahill.
BMC Public Health 2008;8:126

 

openaccess newDifferences in atherosclerosis according to area level socioeconomic deprivation: cross sectional, population based study.
Kevin A Deans, Vladimir Bezylak, Ian Ford, G David batty, Harry Burns, Jonathan Cavanagh, Eric De Groot, Agnes McGinty, Keith Millar, Paul G Shiels, Carol Tannahill, Yoga N Velupillai, Naveed Sattar, Chris J Packard.
British Medical Journal 2009;339:b4170

 

openaccess newEarly life socioeconomic adversity is associated in adult life with chronic inflammation, carotid atherosclerosis, poorer lung function and decreased cognitive function: a cross-sectional, population based study.
Chris J Packard, Vladimir Bezylak, Jennifer S McLean, G David Batty, Ian Ford, Harry Burns, Jonathan Cavanagh, Kevin A Deans, Marian Henderson, Agnes McGinty, Keith Millar, Naveed Sattar, Paul G Shiels, Yoga N Velupillai, Carol Tannahill.
BMC Public Health 2011;11:42

 

openaccess newAccelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort.
Paul G Shiels, Lianne M McGlynn, Alan MacIntyre, Paul CD Johnson, G David Batty, Harry Burns, Jonathan Cavanagh, Kevin A Deans, Ian Ford, Alex McConnachie, Agnes McGinty, Jennifer S McLean, Keith Millar, Naveed Sattar, Carol Tannahill, Yoga N Velupillai, Chris J Packard.
PLoS ONE 2011; 6(7):e22521

 

Socio-economic status is associated with epigenetic differences in the pSoBid cohort. 
Dagmara McGuinness, Liane M McGlynn, Paul CD Johnson, Alan MacIntyre, David G Batty, Harry Burns, Jonathan Cavanagh, Kevin A Deans, Ian Ford, Alex McConnachie, Agnes McGinty, Jennifer S McLean, Keith Millar, Chris J Packard, Naveed A Sattar, Carol Tannahill, Yoga N Velupillai, Paul G Shiels
International Journal of Epidemiology 2012;1-10 

NOTE - this article is not Open Access and requires Athens or similar password for access 

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